【简介】博士后招聘网整理分享“英国牛津大学2022年招聘博士后职位（发育与再生医学）”，浏览查询更多博士后招聘计划请访问博士后招聘网。

英国牛津大学2022年招聘博士后职位（发育与再生医学）

Research Assistant in Developmental and Regenerative Medicine

University of Oxford

Description

Department of Paediatrics, Institute of Developmental and Regenerative Medicine (IDRM), Old Road Campus, Oxford

Applications are invited for a research assistant post, to join a team working with Dr. Rebecca Berrens at the newly established Institute, IDRM, Oxford.

We are interested in the functional role of transposable elements in cell fate decision during early development and in cellular regeneration. The role of transposable elements (TEs) in gene regulation during cell fate decision has largely remained elusive. Most TEs have lost their ability to insert additional copies into new genomic locations, however TEs make up 50% of the mammalian genome and harbour regulatory elements that can affect gene expression. Consequently, TEs are kept transcriptionally silent in most somatic cells by epigenetic modifications (Berrens et al., Cell Stem Cell, 2017). But these modifications are lifted during cell fate decision, hence TEs are expressed. Despite progress in our understanding of TE expression, a systematic analysis of the role of locus-specific TE expression during cell fate decision has yet to be performed. Moreover, potential patterns of altered TE expression in disease states are yet to be investigated.

We aim to interrogate the role of transposable elements in cell fate decision by combining CELLO-seq (Berrens et al., Nature Biotechnology, 2022) - our novel single cell long read sequencing technology - with state-of-the-art gene editing technologies.

We are looking for a talented and enthusiastic researcher to join our team and to work alongside Dr Berrens, who is further developing and adapting technologies like single-cell long read transcriptomics, imaging and genome- editing approaches. You will work on embryonic stem cells as well as models of cellular differentiation and will be involved in the continued effort of adapting these state-of-the-art technologies to interrogate the role of Transposable elements in cell fate decision.

The post is ideally suited for a candidate with an interest in developing a career that involves working at the interface of Developmental Biology, Immunology and Regenerative Medicine.

This post is full time and fixed term until 31 July 2024.

You will be required to upload a CV and Supporting Statement as part of your online application. The Supporting Statement should include a cover letter and should also clearly describe how you meet each of the selection criteria listed in the job description. Click here for information and advice on writing an effective Supporting Statement.

To discuss post in more detail please contact Rebecca Berrens, IDRM Transition Fellow, using the contact details below.

Only online applications received before 12.00 midday on Tuesday 20 September will be considered. Interviews will be held as soon as possible thereafter.

Contact Person : Rebecca Berrens Vacancy ID : 160086 Contact Phone : Closing Date & Time : 20-Sep-2022 12:00 Pay Scale : STANDARD GRADE 6 Contact Email : rebecca.berrens@paediatrics.ox.ac.uk Salary (£) : £30,502 - £36,386 per annum (with a discretionary range to £39,745 per annum)

更多最新博士后招收信息请关注博士后招聘网微信公众号（ID：boshihoujob）

祝君：学业有成、学成归来

请您在邮件申请时在标题注明信息来自：博士后招聘网-boshihoujob.com，电话咨询时说明从博士后招聘网(www.boshihoujob.com)看到的博士后招聘信息。

声明：凡本网注明“来源：XXX”的文/图等稿件，本网转载出于传递更多信息及方便产业探讨之目的，并不意味着本站赞同其观点或证实其内容的真实性，文章内容仅供参考。如其他媒体、网站或个人从本网站转载使用，须保留本网站注明的“来源”，并自负版权等法律责任。作者如果不希望被转载或者联系转载等事宜，请与我们联系。邮箱：boshihoujob@163.com。