英国约克大学2023年招聘博士后（昆虫合成生物学）

约克大学（University of York），建于1963年，位于英国英格兰约克，是一所公立研究型大学。

约克大学是英国罗素大学集团、世界大学联盟、N8大学联盟、白玫瑰大学联盟和江苏—英国高水平大学联盟成员。该校校友中有15位英国议会议员。

约克大学位列2023QS世界大学排名162位，2024THE世界大学排名第147位。

Postdoctoral Research Associate OR Postdoctoral Research Fellow

University of York

United Kingdom

January 03, 2024

Contact:N/A

Offerd Salary:£36,024 - £44,263

Location:N/A

Working address:N/A

Contract Type:Other

Working Time:Full time

Working type:N/A

Ref info:N/A

Postdoctoral Research Associate OR Postdoctoral Research Fellow

Department

Biology

Salary

Grade: £36,024 - £44,263 or Grade 7: £44,263 - £54,395 per year

Grade

Grade 6/7

Contract status

Fixed term

Hours of work

Full-time

Based at

University of York campus

Interview date

To be confirmed

Posted Date

23/11/2023

Apply by

03/01/2024

Job Reference

12883

Documents

· 12883 Job Description (Grade 6).pdf (PDF, 1053.1kb)

· 12883 Job Description (Grade 7).pdf (PDF, 1052.18kb)

Role DescriptionDepartment

The aim of the lab, and of this project, is to use insect synthetic biology to develop new, safe, sustainable methods for reducing the harm caused by pest insects, particularly mosquitoes and mosquito-borne disease. This position is part of a recently initiated five-year project, selected by the European Research Council (ERC Advanced Grants, 欧元2.5m) and now funded by the UK government through EPSRC.

Better methods for controlling mosquito-borne viruses are urgently required. One attractive approach is to release sterile male mosquitoes to mate wild females, thereby reducing their reproductive potential – the Sterile Insect Technique (SIT). The PI previously developed – and successfully took to field use – an improved variant of traditional SIT using engineered mosquitoes to provide “sterile male” properties; other methods of sterilisation are available, e.g. irradiation, use of Wolbachia, each with their advantages and disadvantages. However, SIT requires frequent releases of very large numbers of such males. A radical new SIT variant is proposed, which is sustainable and persistent – SuperSIT. Modelling suggests dramatic (20-100x) reduction in the number of males required. If successfully developed and deployed, this will provide the established (by the PI and others) benefits of effective, environmentally-friendly, species-specific control at much lower cost.

The aim of this project is to develop initial prototype strains and assess their performance in laboratory cage experiments.

RoleGrade 6 Postdoctoral Research Associate OR Grade 7 Postdoctoral Research

Fellow available depending upon qualifications and experience.

The core of the project is to develop and test components, modules and systems for novel sterile-male systems in Aedes aegypti. Correspondingly, the main component of the role is to lead insect genetic studies (design and development of new transgenic/gene edited strains) and molecular biology (design and development of novel plasmids), communicating progress and data including leading manuscript preparation, and training/supervising other staff/students.

Skills, Experience & Qualification needed

· PhD in a relevant biological science, or equivalent. (For the Grade 7 role the successful candidate must have acquired significant postdoctoral experience).

· Track record of research success; supervisory experience

· Good communication skills, ability to write up research work for publication in high profile journals

· Experience of working with insects

· Dependable, reliable and self-motivated; good interpersonal skills; able to work as part of a team

· To contribute to and/or lead on the production of research outputs and research outcomes. (Grade 7)

· To make presentations at conferences or exhibit work in other appropriate events (Grade 7)

Applicants will be considered for both positions unless specifically requested otherwise. This post is available until January 2028.

Interview date: To be confirmed

For informal enquiries: Please contact Prof Luke Alphey (luke.alphey@york.ac.uk)

Biology at York was the first UK Biology Department to achieve Athena Swan Gold Award.

The University strives to be diverse and inclusive – a place where we can ALL be ourselves.

We particularly encourage applications from people who identify as Black, Asian or from a Minority Ethnic background, who are underrepresented at the University.

We offer family friendly, flexible working arrangements, with forums and inclusive facilities to support our staff. #EqualityatYork

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