法国巴黎巴斯德研究所2024年招聘博士后职位（计算生物学）

法国巴斯德研究所成立于1887年，是一个公益型私人基金会。其职能是致力于对疾病的预防和治疗的科学研究、培训和其它公共卫生行为。它既是生物学基础性研究中心、大学后教学中心（研究与诊断培训），又是专门的生物医学中心、传染病专科住院中心、热带病理学和免疫系统疾病中心。巴斯德研究所包括一个历史展馆、一个科学展馆和一个新建的以图书馆为主体的科学信息中心。

Institut Pasteur Paris

Postdoctoral Position in Computational Biology

The ParSig team (https://research.pasteur.fr/en/team/molecular-parasitology-and-signaling/) at the Institut Pasteur in Paris seeks for a highly qualified computational biologist at the senior postdoc/research assistant level to join the ERC Synergy project DecoLeishRN (https://cordis.europa.eu/project/id/101071613). The successful candidate should have at least 3 years of postdoc experience in the fields of bioinformatics and population genetics and should be motivated to establish a cutting-edge project that will serve as a springboard to independence. The selected candidate will join and collaborate with a vibrant, international team that applies experimental evolution to study mechanisms of fitness gain in the eukaryotic pathogen Leishmania. In particular, the candidate will (i) apply and further develop our previously established bioinformatics pipeline (GIP, Bussotti et al., NAR 2022, http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8989552/), (ii) integrate various large data sets generated by short-read, long-read and single cell DNAseq and RNAseq analyses during parasite evolution in vitro and in vivo, and (iii) establish new computational tools in collaboration with local resources and with our partner at the Weizmann Institute of Sciences to study the evolution of regulatory networks underlying Leishmania fitness gain. Wet lab experience is not required, but a solid background in biology will be of advantage. Interested candidates should send a motivation letter, CV (including 3 names for references) and list of publications to gerald.spaeth@pasteur.fr. This call will be open until a suitable candidate has been recruited.

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