美国加州大学圣迭戈分校2024年招聘博士后职位（RNA生物学与RNA疗法）

加利福尼亚大学圣迭戈分校（University of California，San Diego；简称UCSD或UC San Diego），位于美国圣迭戈的海滨城镇拉荷亚（La Jolla），一所公立研究型大学，环太平洋大学联盟、国际公立大学论坛和美国大学协会成员，入选英国政府“高潜力人才签证计划”。

Single Cell Analyses of Human and Nonhuman Primate Brains and RNA Therapeutics

University of California, San Diego

Available immediately for highly motivated recent PHDs and/or MDs with strong training in any of the following disciplines: biochemistry, bioinformatics, immunology, neuroscience, molecular and cell biology, virology, medicinal chemistry or chemical biology to participate in any of the following projects involving multidisciplinary teams of translational and basic science investigators: (a) innovative single-cell studies to generate cellular part list for human and nonhuman primates brain regions illuminating novel insights into transcriptomic and epigenetic landscapes of CNS and how their functions are altered by viruses and drugs; (b) designing and evaluating new RNA vaccines and gene therapies; (c) investigate RNA biology mechanisms in immune functions and changes by RNA viruses and cancer; (d) identify epitranscriptomics roles in regulating cancer and host-pathogen interactions; (e) develop and employ human stem cell derived 3D organoids and stem cell based disease models; (f) structure-based design and synthesis of new drug candidates, lipid nanoparticles, to treat cancer and viral infections. Technologies employed in our projects include CRISPR, RNAi, RNA and genes delivery, single cell genomics (scRNA-seq and scATAC-seq), spatial transcriptomics, bioinformatics, in vitro and in vivo models, computational drug design and synthesis, and biochemical kinetics assays to analyze drug activities. Strong publication record and training to perform independent research are required for further consideration. We highly value and encourage applicants from underrepresented minority groups. For examples of our multidisciplinary research program and technologies used in our work, see https://ranalab.ucsd.edu and Rana Lab Publications. Successful Candidates will be part of a stimulating and collaborative scientific environment with cutting-edge instrumentation and facilities. Applicants should send CV and names and addresses of three references to ranaoffice@ucsd.edu: Administrative Coordinator, Rana Laboratory, Division of Genetics, Program in Immunology, Bioinformatics and Systems Biology Program, Moores Cancer Center, Institute for Genomic Medicine, and Center for Drug Discovery Innovation, University of California San Diego, La Jolla, California, USA.

The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to gender, race, color, religion, sex, national origin, disability, age or protected veteran's status.

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