美国密歇根大学2024年招聘博士后（肺损伤与再生）

密西根大学（University of Michigan），也称密西根大学安娜堡校区，简称密大或UMich ，创建于1817年，校本部位于美国密西根州安娜堡市，是一所公立研究型大学，被誉为公立常春藤，入选英国政府“高潜力人才签证计划”。

Employer

University of Michigan

Location

Michigan

Salary

Commensurate with experience level and institutional payscale

Closing date

Sep 2, 2024

Postdoc/Senior Scientist/Research Faculty Position Available

Seeking a postdoctoral fellow, senior staff scientist, or research faculty to join a dynamic and growing lab focused on lung injury and regeneration.

Research Interests

Our lab is interested in understanding the mechanisms by which the lung epithelium responds to injury. We study mechanisms of injury/inflammation and regeneration after injury. Epithelial injury and a failure of epithelial regeneration is thought to drive the development of lung diseases such as ARDS (including COVID-19), fibrosis, and emphysema. Specifically, we are exploring the mechanisms underlying proliferation and differentiation of alveolar epithelial progenitor or stem cells. We have identified β-catenin, HIF, and TGFβ signaling as important drivers. We also study the epithelial inflammatory and host defense responses to bacterial and viral infection, specifically epithelial-immune cell crosstalk. We use mouse and cell culture models to study mechanisms. The mouse work involves lineage tracing and inducible cell-specific gene deficient mice, and primary epithelial cell culture/organoid work allows us to further dissect mechanism. We use confocal imaging, immunostaining, fluorescence in situ hybridization (FISH), single cell RNA sequencing, proteomics, and flow assisted cytometry sorting (FACS). We aim to address important questions and make novel discoveries that significantly enhance out understanding of lung biology and disease. We hope that our discoveries may ultimately lead to the development of therapies for infectious, inflammatory, and fibrotic lung diseases..

Lab Website: https://sites.google.com/view/rachelzemanslab/home

Description of Position

The scientist will be expected to take a leading role and work closely with the PI in the development and implementation of this research program. A PhD (completed or near completion) or MS or BS with significant experience in cell biology, developmental biology, immunology, physiology, or related field is required. Outstanding organizational skills, attention to detail, ability to work hard and be flexible in a fast-paced environment, and ability to get along with other lab members are important. Prior experience with rodents, cell culture, microscopy, RNA/qPCR, western blotting, computational biology, and/or flow cytometry would be helpful. At least one first authored manuscript in a peer-reviewed journal is required for candidates with a PhD. Candidates interested in either leading their own projects or supporting projects of other team members are encouraged to apply.

Excellent opportunity for individuals interested in studying stem cells and tissue regeneration as well as immune-epithelial crosstalk. Projects range from basic mechanistic to translational. Opportunities to learn cutting-edge techniques, including organoid culture and scRNAseq. Opportunities for career development, including manuscript and grant writing and oral presentation, mentorship, attending international conferences, interacting with renowned scientists who are collaborators.

How To Apply. Please send cover letter, CV, and references to zemansr@med.umich.edu.

更多最新博士后招聘信息请关注博士后招聘网微信公众号（ID：boshihoujob）

祝君：学业有成，学成归来。

请您在邮件申请时在标题注明信息来自：博士后招聘网-boshihoujob.com，电话咨询时说明从博士后招聘网(www.boshihoujob.com)看到的博士后招聘信息。

声明：凡本网注明“来源：XXX”的文/图等稿件，本网转载出于传递更多信息及方便产业探讨之目的，并不意味着本站赞同其观点或证实其内容的真实性，文章内容仅供参考。如其他媒体、网站或个人从本网站转载使用，须保留本网站注明的“来源”，并自负版权等法律责任。作者如果不希望被转载或者联系转载等事宜，请与我们联系。邮箱：boshihoujob@163.com。