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Postdoctoral Research Assistant : Bristol, United Kingdom

Postdoctoral Research Assistant

Vacancy number: ACAD101147

School of Cellular and Molecular Medicine

£31,342 starting

A 3 year post funded by the Neuroblastoma Society in conjunction with Smile With Siddy is available to examine novel mechanisms for destabilizing the MYCN oncoprotein in neuroblastoma (NB) cells. As approximately half of poor prognosis NB is characterised byMYCN over-expression, therapeutic targeting of MYCN represents a great opportunity for treating NB. Recently, promising small molecule inhibitors which can lead to depletion of MYCN have been reported [seehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784814/].

This project will utilise proteomic and molecular biology techniques to characterise new pathways involved in regulating MYCN, and assess novel drugs that may target these pathways. Candidates should have a strong background in cancer biology and therapeutics, together with broad technical expertise pertinent to the aims of the project.

For informal enquiries, please contact Dr Karim Malik on 0117-3312078.

The University of Bristol is committed to equality and we value the diversity of our staff and students.

To apply, please click on the Apply button to be redirected to our website, enter the vacancy number into the job search and follow the link to the on line application process.

The closing date for applications is Sunday 4th January 2015.

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