德国亥姆霍兹协会癌症研究中心（DKFZ）2025年博士后招聘（胰腺癌免疫学和计算生物学）

2 Postdoc Positions in Pancreatic Cancer Immunology and Computational Biology

Employer

German Cancer Research Center in the Helmholtz Association (DKFZ)

Location

Munich (Stadt), Bayern (DE)

Salary

Remuneration according to TV-L incl. occupational pension plan and capital-forming payments

Closing date

24 May 2025

Website

https://www.dkfz.de/

Job Details

„Research for a life without cancer“ is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts – whether in research, administration or infrastructure. This is what makes our daily work so meaningful and exciting.

Together with university partners at seven renowned partner sites, we have established the German Cancer Consortium (DKTK).

The Department of Translational Cancer Research and the Institute of Experimental Cancer Therapy at the DKTK partner site Munich is offering for as soon as possible

2 Postdoc Positions in Pancreatic Cancer Immunology and Computational Biology

Reference number: 2025-0105

We are deploying advanced in vitro and in vivo model systems, genetic perturbations and single cell technologies with spatial readouts to study the distinct routes of tumor evolution and modes of immunosuppression we identified in our previous work in subtypes of pancreatic cancer (e.g., Nat Commun. 2023 14:2642 and 14:1201; Nature Cancer 2022 3:318-336, Cancer Discovery 2021 11:3158-3177,(For more postdoctoral recruitment information, visit:boshihoujob.com) Nature 2018 554:62-68; Nat. Rev. Cancer 2017 17:239-253; Nat. Commun. 2016, 7:10770; Nat Med. 2014, 20:1340-7). During the past decade, our lab has generated a comprehensive resource of pancreatic primary tumors and primary cell cultures. Multiple NGS methods and biological readouts have been conducted to decipher the molecular makeup and phenotypes of these tumors. The advertised projects focus on (1) unraveling targetable nodes of the cancer-immune niche and its impact on treatment response and resistance, (2) understanding the contribution of cancer associated fibroblasts towards immunosuppression, and (3) developing computational single cell and spatial transcriptomics pipelines to investigate tumor subtype specific genetic interactions in close collaboration with the Theis lab at Helmholtz Center Munich.

We are an enthusiastic and international team and offer intensive training and mentoring.

The Department of Translational Cancer Research and the Institute of Experimental Cancer Therapy at the DKTK partner site Munich is seeking two postdocs to join the group as soon as possible.

Your Tasks:

The successful candidates will have the opportunity to:

Gain important insights into clinically relevant aspects of cancer development and therapy

Perform state-of-the-art in vivo experiments and large-scale drug and genetic screens

Learn and apply a wide spectrum of genetic, molecular and cell biology, biochemical as well as immunological and bioinformatics techniques to study translational aspects of cancer (e.g. Cre/loxP and Flp/FRT based dual- and triple recombinase systems, organoid culture, orthotopic transplantations of cells/organoids, CRISPR/Cas9, molecular in vivo imaging, quantitative proteomics/phosphoproteomics, multiple transcriptomics and genomics approaches, single cell sequencing, histocytometry)

Set up bioinformatics platforms and develop computational pipelines for the analysis of bulk and single cell RNA-sequencing, DNA-sequencing datasets and proteomics

Integrate these datasets with molecular (WES, WGBS, lcWGS, ChIPseq, ATACseq), phenotypic (e.g. histology), drug screening and clinical information

Interact within a diverse and multidisciplinary environment of biologists, clinicians, computational scientists and mathematicians within the TranslaTUM.

Your Profile:

We are looking for exceptional self-motivated bright individuals with a Diploma or Master’s degree in bioinformatics, biochemistry, biology, molecular/translational medicine or related subjects. Previous exposure to and experience with basic biochemical and molecular biology techniques, proteomics or bioinformatics as well as interests in molecular aspects of cancer research are essential. Due to the interdisciplinary framework and close collaboration between wet-lab and computational scientists, good communicative skills in English are essential. German language skills are not required.

Interested candidates should send one pdf file with a CV, cover letter, certificates, and letters of recommendation.

We Offer:

Excellent framework conditions: state-of-the-art equipment and oppor­tunities for inter­national networking at the highest level

Remuneration according to TV-L incl. occupational pension plan and capital-forming payments

30 days of vacation per year

Flexible working hours

Possibility of part-time work

Family-friendly working environ­ment

Sustainable travel to work: subsidized Germany job ticket

Our Corporate Health Management Program offers a holistic approach to your well-being

Develop your full potential: access to the DKFZ International Postdoc Program and DKFZ Career Service with targeted offers for your personal development to further develop your talents

Contact:

Prof. Dr. Dieter Saur

Phone: +49 89 4140 9130

The positions are initially limited to 2 years with the possibility of prolongation.

Are you interested?

Then become part of the DKFZ and join us in contributing to a life without cancer!

Apply now

We are convinced that an innovative research and working environment thrives on the diversity of its employees. Therefore, we welcome applications from talented people, regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical ability, religion and age. People with severe disabilities are given preference if they have the same aptitude.

Notice: We are subject to the regulations of the Infection Protection Act (IfSG). Therefore, all our employees must provide proof of immunity against measles.

Share this job!

Deutsches Krebsforschungszentrum | Im Neuenheimer Feld 280 | 69120 Heidelberg | www.dkfz.de

更多最新博士后招聘信息请关注博士后招聘网微信公众号（ID：boshihoujob）

祝君：学业有成，学成归来。

请您在邮件申请时在标题注明信息来自：博士后招聘网-boshihoujob.com，电话咨询时说明从博士后招聘网(www.boshihoujob.com)看到的博士后招聘信息。

声明：凡本网注明“来源：XXX”的文/图等稿件，本网转载出于传递更多信息及方便产业探讨之目的，并不意味着本站赞同其观点或证实其内容的真实性，文章内容仅供参考。如其他媒体、网站或个人从本网站转载使用，须保留本网站注明的“来源”，并自负版权等法律责任。作者如果不希望被转载或者联系转载等事宜，请与我们联系。邮箱：boshihoujob@163.com。