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Postdoc in porcine cytotoxic T Cell immunology : Frederiksberg, Denmark

Postdoc in porcine cytotoxic T Cell immunology

The National Veterinary Institute (DTU Vet) invites applicants for a 2-year postdoc position at The Section of Immunology and Vaccinology. The focus of the position is on the characterization and quantification of cytotoxic T cell responses in porcine immunology with special reference to the use of pigs as a large animal model for human diseases and in the development of new vaccines tailored to induce a CTL response.

Responsibilities and tasks
Together with colleagues and collaborators from other institutes, universities and companies, the candidate is expected to advance the current state-of-the-art in porcine CTL immunology.

Research will focus on development and application of methods to improve the understanding ofCTL induction and regulation with special relation to:

-Identify peptide-binding motifs of SLA-alleles by in vitro binding assays with synthetic peptides and recombinantly produced SLA molecules and by MS analysis of eluted peptides after in vivo binding
-Quantify peptide-specific effector CTL by IFN-γ ELISPOT or flow cytometry
-Use multimers of recombinantly produced SLA molecules to detail peptide-specific CTL by flow cytometry
-Development and use of methods to identify antigen epitopes bound by CD1 molecules
-Contribute to the design of new vaccines with enhanced CTL induction and validation of their efficacy.

The position is established in relation to a strategic initiative focused on using the pig as model for human disorders. It will involve collaborative research with leading Danish and International academic groups.

Qualifications
Mandatory requirements:

-PhD degree in immunology or biochemistry as well as academic qualifications equivalent to those obtained by holding a position as Researcher or Postdoc
-Expertise in T cell immunology
-Expertise in flow cytometry
-High quality publication record
-International experience
-Strong work ethic and motivation to succeed within a competitive research field

Preference given to candidates with strong experience in:

-Porcine Immunology
-MHC technologies such as peptide-MHC binding assays and assembly of MHC-tetramers

We offer
an interesting and challenging job in an international environment focusing on research, education, public-sector consultancy and innovation, which contribute to enhancing animal and human health. We strive for academic excellence, collegial respect and freedom tempered by responsibility. The Technical University of Denmark (DTU) is a leading technical university in northern Europe and benchmarks with the best universities in the world.

Salary and terms of employment
The appointment will be based on the collective agreement with the Confederation of Professional Associations. The allowance will be agreed with the relevant union.

The position is for 2 years.

The place of work will be The National Veterinary Institute, Bülowsvej 27, 1870 Frederiksberg C.

We expect the candidate to start 1 August 2014.

Further information
Further information may be obtained from Head of Section Jørgen Schøller, mail:jorsch@vet.dtu.dk, +45 3588 6217.

Please do not send applications to this e-mail address, instead apply online as described below.

You can read more about DTU Vet at www.vet.dtu.dk

Application procedure:
Please submit your online application no later than 1 May 2014. Apply at www.career.dtu.dk

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online," fill in the online application form, and attach all your materials in English in one PDF file. The file must include:

-Application (cover letter)
-CV
-Diploma
-List of publications

The material that should be given consideration in the assessment must be attached.

Applications and enclosures received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

DTU is a technical university providing internationally leading research, education, inno- vation and public service. Our staff of 5,000 advance science and technology to create innovative solutions that meet the demands of society; and our 10,000 students are educated to address the technological challenges of the future. DTU is an independent academic university collaborating globally with business, industry, government, and public agencies.

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