【简介】博士后招聘网整理分享“巴西圣保罗大学招收细胞生物学博士后”，浏览查询更多博士后招聘计划请访问博士后招聘网。

Research associte : SAO PAULO, Brazil

Biomarkers of redox misbalance induced by UVA and VIS radiation on XPC fibroblasts and melanocytes

Area: Biochemistry
PI: Mauricio da Silva Baptista
Department of Biochemistry, Institute of Chemistry, USP, Brazil.

Abstract: Protection of human skin against sun exposition is a complex issue that involves ambivalent aspects of the interaction of light with tissues. Both UVA and visible radiation causes redox misbalance and cell damage. UVA is considered a class I carcinogen while visible is not, although our and other research groups have provided evidence that it should be considered as such. One of the problems that hinders the proper characterization of the effects of radiation in both UVA and visible is the lack of molecular knowledge that links redox misbalance and mutagenic DNA products. On this project we will use cells models that tend to accumulate the products of redox misbalance because of the lack of DNA repair (XPC fibroblasts) and because of the generation of a stronger burst of redox misbalance (melanocytes with over-expression of melanin). We will use these extreme conditions to identify by mass spectrometry biomarkers that can link the redox misbalance with the mutagenicity.

Background expected from the applicant: experience with cellular biochemistry and mass spectrometry.

Selection: Based on the analysis of CV and letters of recommendation.
Documents for application: Letter justifying interest for the project, cv, copy of doctorate certificate, recommendation letters.

Send application to: Prof. Mauricio S. Baptista at baptista@iq.usp.br

请您在邮件申请时在标题注明信息来自：博士后招聘网-boshihoujob.com，电话咨询时说明从博士后招聘网(www.boshihoujob.com)看到的博士后招聘信息。

声明：凡本网注明“来源：XXX”的文/图等稿件，本网转载出于传递更多信息及方便产业探讨之目的，并不意味着本站赞同其观点或证实其内容的真实性，文章内容仅供参考。如其他媒体、网站或个人从本网站转载使用，须保留本网站注明的“来源”，并自负版权等法律责任。作者如果不希望被转载或者联系转载等事宜，请与我们联系。邮箱：boshihoujob@163.com。