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Postdoctoral Researcher for single cell analysis of human T cell development : Ghent, Belgium

Description
The research group of Prof. Tom Taghon, located in Ghent, Belgium, is looking for a talented and highly motivated postdoctoral researcher to join our team. The focus of the lab is to characterize the molecular mechanisms that control the stepwise differentiation of human hematopoietic stem cells into T lymphocytes. While it has clearly been established that the earliest stages of T cell development in human are characterized by unique changes in cell surface marker expression that differ from more frequently used model organisms such as mice, evidence now emerges that also the molecular mechanisms that drive these developmental processes differ between these species. Using human primary T cell precursors, successful candidates will apply state-of-the-art single cell approaches, including RNAseq, flow cytometric RNA detection probes and in vitro cell culture assays with the specific goal to identify and characterize the earliest stages of human T cell development and to obtain novel perspectives on the molecular drivers (including non-coding RNAs) that control the stepwise conversion of hematopoietic stem cells into T lymphocytes. You will work together with an international group of postdocs, PhD students and technicians in a new research building on the Ghent University Hospital campus that houses leading research groups in the field of Immunology and Genetics, thereby providing a state-of-the-art and stimulating research environment.

Profile
Candidates should have a relevant PhD in the field of immunology, developmental biology, bioinformatics or related. You have excellent knowledge and skills in molecular biology and preferentially also in bioinformatics and RNAseq data analysis. Expertise in cell culture and flow cytometry is a plus. You are highly motivated and a team player with good reporting and writing skills in English. Applicants should have a competitive publication record in peer-reviewed international journals with at least one paper as a first author. International candidates with less than 3 years of postdoc experience are especially encouraged to apply.

Applications
For further information or to apply (include motivation letter, contact details of 2-3 referees and curriculum vitae with publication list and research experience), please contact : Prof. Dr. Tom Taghon (E-mail: Tom.Taghon@UGent.be) …

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