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Computational Biologist - Genomics : Milan, Italy

One postdoctoral position for a computational biologist to work on the epigenetic and transcriptional control of inflammation and cancer is available at the European Institute of Oncology (IEO), Milan.

We are looking for a highly motivated scientist with a strong interest in transcriptional regulation and epigenetics. The successful candidate will be in charge of next-generation sequencing data analysis and integration.

Computational programming skills are required.

Competitive salary, commensurate with experience and track record, and benefits.

Please send a CV, a one-page statement of research interest and contact information for two-three referees to Gioacchino Natoli at gioacchino.natoli@ieo.eu

Recent publications from the lab:
1. Coregulation of transcription factor binding and nucleosome occupancy by DNA features of mammalian enhancers. Molecular Cell (advance online publication) (2014)

2. Latent enhancers activated by stimulation in differentiated cells. Cell. 152: 157-71 (2013).Hdac3 requirement for the inflammatory gene expression program Proc Natl Acad Sci USA109:E2865-74 (2012)

3. The histone methyltransferase Mll4 controls macrophage function through glycosylphosphatidylinositol anchor synthesis. Immunity 36, 572-585 (2012)

4. A large fraction of extragenic RNA Pol II transcription sites overlap enhancers. PLoS Biology 8(5): e1000384. doi:10.1371/journal.pbio.1000384 (2010).

5. Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages. Immunity, 32:317-28. Epub 2010 Mar 4 (2010).

6. Non-cooperative interactions between transcription factors and clustered DNA binding sites enable graded transcriptional responses to environmental　inputs. Molecular Cell37, 418-428 (2010)…

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