【简介】博士后招聘网整理分享“美国MD安德森癌症中心癌症纤维细胞研究博士后职位”，浏览查询更多博士后招聘计划请访问博士后招聘网。

Our goal is to understand how cancer-associated fibroblasts (CAFs) drive the malignant progression of lung cancer by functioning as pericytes. We use cell co-culture systems in which CAFs exhibit pericytic properties, secrete a collagen-rich matrix, and communicate bi-directionally with tumor cells, endothelial cells, and macrophages to create vessels and regulate tumor cell migration and invasion. These cells are derived from genetically-engineered mice that express vascular reporters and develop lung adenocarcinoma that are highly fibrotic and infiltrated by CAFs that produce collagen and a plethora of pro-inflammatory and pro-angiogenic cytokines. For validation studies, we use a large bank of human lung cancers annotated for somatic oncogenic mutations and clinical variables. This is a highly collaborative project with a multi-disciplinary group of investigators at MD Anderson Cancer Center, Baylor College of Medicine, and Rice University who are funded by NIH and other agencies to address this question.

请您在邮件申请时在标题注明信息来自：博士后招聘网-boshihoujob.com，电话咨询时说明从博士后招聘网(www.boshihoujob.com)看到的博士后招聘信息。

声明：凡本网注明“来源：XXX”的文/图等稿件，本网转载出于传递更多信息及方便产业探讨之目的，并不意味着本站赞同其观点或证实其内容的真实性，文章内容仅供参考。如其他媒体、网站或个人从本网站转载使用，须保留本网站注明的“来源”，并自负版权等法律责任。作者如果不希望被转载或者联系转载等事宜，请与我们联系。邮箱：boshihoujob@163.com。