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Sylvester Comprehensive Cancer Center Miami, Florida (US) Commensurate with Experience

We are looking for a Postdoctoral Associate candidate to work closely with the principal investigator.

Research in the laboratory of Dr. Ramin Shiekhattar a leader in epigenetics and RNA biology fields is centered on identifying mechanisms and factors involved in enhancer function and enhancer deregulation in pancreatic cancer and melanoma using novel tools and methods toward enhancer therapy in cancer. These will include dissecting the role of enhancer RNAs (eRNAs) and long noncoding RNAs (lncRNAs) in enhancer function and cancer progression.

Successful applicants will work on projects aimed at identifying and verifying the function of enhancer regulatory proteins and other epigenetic factors, during pancreatic and skin cancer progression. Moreover, the applicants will be involved in projects related to understanding the role of Integrator proteins in gene regulation, chromatin dynamics, and cell-fate determination.

The group is using state-of-the-art techniques and model systems to achieve these goals, including protein loss-of-function (shRNA, CRISPR/Cas9), embryonic and adult stem cells, cancer cell lines and patient-derived cell lines and tumors, proteomic analysis (mass-spectrometry), and global genomics and transcriptomics technologies (RNA-seq, ChIP-seq).

Qualifications

We are looking for highly motivated, ambitious candidate with a strong interest in epigenetics, cancer and stem cells. In addition, the successful candidate should have: 

• A PhD in Life Sciences

• Proven track record of publication in international journals.

• Previous experience in biochemistry, stem cell and/or cancer biology.

• Excellent written and oral communication skills. Fluency in English is compulsory.

• The wish to be part of a highly interactive and international group of scientists.

Place of employment

Our lab is located at the Sylvester Comprehensive Cancer Center (SCCC), University of Miami Miller School of Medicine (http://medgen.med.miami.edu/shiekhattar). We offer creative and stimulating working conditions in a dynamic and international research environment. We have weekly journal clubs, data clubs and seminars with invited speakers.

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