【简介】博士后招聘网整理分享“英国达世药业有限公司2020年博士后招聘（创新药物研发方向）”，浏览查询更多博士后招聘计划请访问博士后招聘网。

英国达世药业有限公司2020年博士后招聘（创新药物研发方向）

Job Title: Sustaining Innovation Postdoctoral Research Associate

Project Title: Development of ligand docking software for X-ray and cryo-EM experimental maps

Job Type: 3 Year Fixed Term Contract, Full Time

Location: Cambridge, UK

Astex Pharmaceuticals is a world leader in innovative drug discovery and development. The company has successfully applied its proprietary Fragment-Based Drug Discovery platform to generate multiple new drug candidates that are progressing in clinical development. Successful collaborations have led to two launched oncology drugs (Kisqali® partnered with Novartis and BalversaTM partnered with Janssen). Astex continues to grow and focuses on Oncology and Neurological Disorders.

The Astex Sustaining Innovation Postdoctoral research program has a track record of performing cutting-edge research and development and is a key element of our excellent scientific culture. During your SI Postdoc project you will be exposed to a multi-disciplinary pharma environment. You’ll benefit from our internal training seminars that will enhance your understanding of the drug discovery process. As part of your career development, you will have the opportunity to present your work within the company and at external meetings and you’ll be expected to publish your findings in high-impact journals.

A postdoctoral position is available within the Molecular Sciences department to develop automated ligand docking guided by experimental electron density maps. The project will focus on improving the sensitivity, accuracy and scope of the methods and pipelines that we have available in-house for automated small molecule ligand fitting into protein structures using electron density maps determined by X-ray crystallography. This will include developing new algorithms (potentially including AI), improving methods for fitting complex ligands and exploring the potential utility of methods for use with cryo-electron microscopy. Any new methods and/or pipeline will be benchmarked using publicly available datasets and a proprietary Astex data repository containing over 10000 protein-ligand complexes.

Candidate Requirements

· PhD in crystallography, structural biology, computing, or a related discipline

· Good understanding of protein-ligand interactions

· Familiarity with ligand docking

· Experience with crystallographic computing is a plus

· Expert knowledge in Python

· Experience with artificial intelligence and cheminformatics is a plus

· Familiarity with common software development tools and practices (version control, testing, etc.)

· Excellent team working, written and verbal communication skills

We offer excellent training and career development opportunities as well as competitive salary and benefits package.

Closing Date: 30th July 2020

To apply please send your CV and a cover letter, quoting the job reference: SI-M003 to hr.uk@astx.com

请您在邮件申请时在标题注明信息来自：博士后招聘网-boshihoujob.com，电话咨询时说明从博士后招聘网(www.boshihoujob.com)看到的博士后招聘信息。

声明：凡本网注明“来源：XXX”的文/图等稿件，本网转载出于传递更多信息及方便产业探讨之目的，并不意味着本站赞同其观点或证实其内容的真实性，文章内容仅供参考。如其他媒体、网站或个人从本网站转载使用，须保留本网站注明的“来源”，并自负版权等法律责任。作者如果不希望被转载或者联系转载等事宜，请与我们联系。邮箱：boshihoujob@163.com。