【简介】博士后招聘网整理分享“瑞典乌普萨拉大学分子医学博士后职位”，浏览查询更多博士后招聘计划请访问博士后招聘网。

Area of responsibilities/description of the work:

The Department of Medical Sciences, Uppsala University, has an opening for one postdoc position focusing on functional characterization of genes involved in obesity and type 2 diabetes-related traits using cell-based techniques.

The work will be done in the research group of Prof. Erik Ingelsson, who leads the section of Molecular Epidemiology at the Department of Medical Sciences, Uppsala University in collaboration with the research group of Prof. Jan Eriksson.

We have identified hundreds of novel susceptibility loci for obesity, lipid levels, glucose and insulin metabolism, and T2D, but the causal gene and mechanisms are unknown for all but a handful of these loci. In the present project, we will use in vitro studies of candidate genes to assess their role in glucose- and insulin metabolism at a cellular level.

We will use siRNA and CRISPR-Cas9 techniques for gene knockdown in adipocytes and skeletal myocytes to study glucose, insulin and lipid metabolism, gene expression and metabolic pathways. Cellular readouts will include basal and insulin-stimulated glucose uptake, insulin signaling, lipolysis and adipogenesis.

Qualifications

To qualify, the applicants must hold a doctor’s degree or a foreign qualification deemed equivalent to a doctorate. Postgraduates who have yet to graduate may apply if their public defense is scheduled to take place within three months after the application deadline, in which case verification from the Dissertation Committee or equivalent body must be submitted with the application.

Prior experience with cell and molecular biology techniques (culture of primary and transformed cell lines, transfection, siRNA, etc), gene editing (bacterial cell culture, cloning, CRISPR-Cas9), real-time PCR,immunoblotting , FACS, ELISA, fluorescent and/or confocal microscopy is

considered favourable. Further experience with metabolic diseases and the cellular readouts listed above is an advantage.

Project employment for one year with a possible extension for a second year.

For further information regarding the position; please contact Professor Erik Ingelsson (erik.ingelsson@medsci.uu.se).

Application

The following documents must be submitted with your application and written in English or Swedish:

1. A full CV, including date of public defense, title of thesis, previous academic appointments, academic title, current position, academic distinctions and committee work; 

2. A full publication list;

3. A brief statement (maximum 1 page) of research interests and goals;

4. Verification from the Dissertation Committee or equivalent body (only if you are planning to defend your thesis within three months after the application deadline);

5. Transcripts of grades from previous education;

6. Names and contact information of three references.

Please note that one copy of all documents will be kept by the university for a period of two years, in accordance with a directive from the National Archives. Unpublished material submitted for review is exempt from this rule.

请您在邮件申请时在标题注明信息来自：博士后招聘网-boshihoujob.com，电话咨询时说明从博士后招聘网(www.boshihoujob.com)看到的博士后招聘信息。

声明：凡本网注明“来源：XXX”的文/图等稿件，本网转载出于传递更多信息及方便产业探讨之目的，并不意味着本站赞同其观点或证实其内容的真实性，文章内容仅供参考。如其他媒体、网站或个人从本网站转载使用，须保留本网站注明的“来源”，并自负版权等法律责任。作者如果不希望被转载或者联系转载等事宜，请与我们联系。邮箱：boshihoujob@163.com。