【简介】博士后招聘网整理分享“英国利兹大学2022年招聘博士后职位（胶质母细胞瘤治疗反应）”，浏览查询更多博士后招聘计划请访问博士后招聘网。

英国利兹大学2022年招聘博士后职位（胶质母细胞瘤治疗反应）

Research Fellow in Glioblastoma Treatment Response

University of Leeds

Description

Applications are invited for a Postdoctoral Research Fellow to join an interdisciplinary team across the Faculties of Medicine and Biological Sciences. You will focus on using a 3D spheroid model of glioblastoma brain cancer to dissect the effect of modifying various molecules (using inhibitors and functional genomic approaches) on response to standard of treatment in this devastating disease. This will lead to prioritisation of those molecules for follow on research into mechanisms that confer treatment response, and how that knowledge can be exploited for patient benefit.

You will benefit from the expertise of molecular, cellular and computational biologists in the application of phenotypic (growth and cell viability) and molecular (phospho-proteomic signalling) assays to, and creation of large ‘omics datasets from, state-of-the-art patient derived in vitro models of glioblastoma. You will have the opportunity to use biopsies from patients undergoing surgery in ex vivo models to additionally test the effect of inhibitors or attempt to optimise gene knockdowns in tissue. This work is ongoing within the group, offering the opportunity to expand the preclinical models used in this current project and further investigate molecules that are candidates for conferring treatment resistance in this incurable cancer. Validating the role of target molecules in altering treatment response, and developing datasets with which to develop insights into the mechanisms of those roles, has the potentially to yield novel and more effective treatments for glioblastoma brain cancer.

You should have a PhD (or be close to completion) in biology or a closely allied discipline, with previous experience in brain cancer research and a track record in experimental approaches to manipulating target molecules and assessing response to both chemotherapeutics and radiation.

To explore the post further or for any queries you may have, please contact:

John Ladbury, Professor of Mechanistic Biology

Tel: +44 (0)113 343 0909 Email: J.E.Ladbury@leeds.ac.uk

Lucy Stead, Dr

Tel: +44 (0)113 343 8410 Email: l.f.stead@leeds.ac.uk

更多最新博士后招收信息请关注博士后招聘网微信公众号（ID：boshihoujob）

请您在邮件申请时在标题注明信息来自：博士后招聘网-boshihoujob.com，电话咨询时说明从博士后招聘网(www.boshihoujob.com)看到的博士后招聘信息。

声明：凡本网注明“来源：XXX”的文/图等稿件，本网转载出于传递更多信息及方便产业探讨之目的，并不意味着本站赞同其观点或证实其内容的真实性，文章内容仅供参考。如其他媒体、网站或个人从本网站转载使用，须保留本网站注明的“来源”，并自负版权等法律责任。作者如果不希望被转载或者联系转载等事宜，请与我们联系。邮箱：boshihoujob@163.com。