首都医学科学创新中心[Chinese Institutes for Medical Research (CIMR), Beijing]（简称创新中心）是北京市2023年11月成立的具有独立法人资格的新型研发机构。作为首都医科大学新校区建设三大板块之一，创新中心以推动医学科学发展、改善人类健康为目标，开展生物医学研究，致力于提升医学科学创新与成果转化能力，提高疾病诊断和治疗水平。我们将汇聚世界高水平科学家，与首都医学教育和科学研究优质资源紧密合作，打造多学科交叉融合的科研平台，综合自由探索、医学目标导向、有组织科研等途径，实践新型科研模式和体制机制，培养适应医学科学创新发展的优秀人才，推进医教研产的深度融合，助力首都医科大学成为世界一流的医科大学。

感染性疾病研究所

创新中心感染性疾病研究所（CIID）致力于推进对感染性疾病的认知与治疗。CIID力求将研究发现转化为药物研发策略与临床应用，为深入理解感染性疾病发生机制及感染性疾病的治疗带来突破性进展。通过汇聚细胞生物学、遗传学、分子和结构生物学领域的顶尖专家，CIID专注于开展前沿研究，并将科学突破转化为切实可行的临床解决方案。我们的使命是通过世界一流的研究和教育来引领微生物致病机制研究的未来方向，最终改善患者预后并拓展治疗可能性。CIID的创始所长是国际知名科学家Gabriel Waksman教授，Waksman教授为欧洲分子生物学组织会员（EMBO）、英国皇家学会院士、德国国家科学院院士。

Waksman实验室

该实验室由感染性疾病研究所创始所长Waksman教授领导。Waksman教授是欧洲结构生物学领域的顶尖学者，其曾获多项殊荣，并入选包括英国皇家科学院（英国国家科学院）和德国国家科学院在内的多个国家级科学院院士。他致力于研究细菌DNA注射体，旨在揭示其作用机制及如何对其进行抑制。这类膜嵌入系统在抗生素耐药基因于细菌病原体间的传播中起着关键作用，因此其具有重要的生物医学意义。

实验室代表性论文

Williams et al., (2025). Nature comms. 16(1):4906.

K. Macé et al., (2022). Nature, 607, 191-196.

A. Ilangovan et al., (2017). Cell. 169, 708–721.

T. Costa et al., (2016). Cell. 166, 1436–1444.

更多信息请访问：

https://people.ismb.lon.ac.uk/gabriel-waksman/homepage.htm

我们提供一个国际化的、富有创造力且鼓舞人心的工作环境。成功获聘者将受益于我们广泛的合作网络，并有机会立即参与国际项目的研究工作。

博士后：

冷冻电子显微镜方向（2人）

荧光显微镜方向（2人）

一、任职要求

针对冷冻电子显微镜方向的博士后职位，申请人应拥有生物物理学、X射线晶体学、结构生物学、生物化学或相关领域的博士学位，并且最好（但不限于）在冷冻电子显微镜数据采集和处理方面拥有丰富经验。申请人必须具备扎实的分子生物学知识。同时，申请人必须具备英语工作能力，并有意愿进一步提升语言技能。

针对荧光显微镜方向的博士后职位，申请人应具备分子与细胞微生物学或相关领域的博士学位，并且最好在适用于细菌细胞的实时成像的荧光显微镜数据采集与处理方面拥有丰富经验。申请人必须具备扎实的分子生物学知识。同时，申请人必须具备英语工作能力，并有意愿进一步提升语言技能。

二、岗位职责

1. 科研与学术

1) 表征通过接合型IV型分泌系统（T4SS）参与DNA转移的多组分复合物的结构和功能特征。博士后学者需参与设计并开展实验，以明确和解析该转运系统的分子机制。

2) 对于实验设计和结果解读，都需与合作实验室保持广泛的学术交流。

3) 开展独立及合作的科研项目，并撰写研究成果发表论文。

4) 持续更新所在领域或专业方向的知识与认知理解。

5) 将学科领域的前沿进展转化为实际的科研活动。

2. 教学与学习

1) 参与评估博士生的学术水平并协助指导其研究项目。

2) 协助培养博士生的科研技能并推进其项目发展。

3) 监督指导博士生的具体工作。

3. 人员管理与团队合作

1) 管理个人的科研及行政事务，必要时接受指导。

2) 须与同事合作开展联合项目。

3) 与学术同行在共同的研究兴趣领域进行合作。

4) 出席并积极参与相关会议。

5) 承担实验室管理方面的组织职责。

4. 问题解决与影响力

1) 运用新兴的研究技术与方法。

2) 发挥主观能动性与创造力，确定研究方向，开发新的研究方法，并进一步拓宽研究范畴。

3) 运用专业知识来分析与解读研究数据，并据此得出研究结论。

4) 在科研领域与同事协作，共同参与决策。

三、福利待遇

1. 根据应聘者的工作经验和能力，提供具有市场竞争力的薪酬（详情面谈）；

2. 享受五险一金、带薪年假、体检和补充医疗保险等；

3. 支持个人职业发展，提供必要的工作相关专业培训。

四、申请方法

申请者请将以下材料（均使用英文撰写）：个人简历、主要成果简要概述、三位推荐人的姓名及联系方式、以及其他能证明科研能力的材料发送至 gabriel.waksman@cimrbj.ac.cn，邮件主题格式为“具体应聘岗位+应聘者姓名+博士后招聘网”。

联系地址：北京市丰台区右安门外西头条10号-首都医学科学创新中心

本招聘长期有效，至招聘到合适人选为止。

ABOUT CIMR

Chinese Institutes for Medical Research (CIMR), Beijing is a research institution committed to advancing basic and translational medical research. Founded in November 2023 as one of the three core pillars of the newly established Capital Medical University, CIMR focuses on addressing fundamental issues in human health by leveraging cutting-edge technologies and conducting interdisciplinary collaborations with world-class scientists and clinicians based in Beijing. CIMR also offers outstanding education and training programs for the next generation of medical scientists. Adhering to a science-oriented governance and operational framework to drive innovation in research and education, we are dedicated to helping Capital Medical University to become a world-class leading medical university.

ABOUT CIID @CIMR

The Chinese Institute for Infectious Diseases at CIMR is committed to advancing knowledge and treatment of infections. CIID strives to translate research discoveries into drug development strategies and clinical applications, paving the way for groundbreaking advancements in our understanding of pathological processes and treatments of infections. By bringing together leading experts in cell biology, genetics, molecular and structural biology, CIID is dedicated to conducting cutting-edge research and transforming scientific breakthroughs into real-world clinical solutions. Our mission is to shape the future of microbial pathogenesis through world-class research and education, ultimately improving patient outcomes and expanding therapeutic possibilities. The founding director of CIID is Professor Gabriel Waksman, an internationally renowned scientist, member of EMBO, Fellow of the Royal Society, and Member of the German Academy of Sciences.

The Waksman Lab

This laboratory is directed by the Founding Director (FD) of the Chinese Institute for Infectious Diseases, Professor Gabriel Waksman. Professor Waksman is a leading scientist in the field of Structural Microbiology. He is the recipient of many awards, and members of numerous National Academies including the prestigious Royal Society (the UK National Academy of Sciences) and the German National Academy of Sciences. He investigates bacterial DNA injectosomes, seeking to understand how they work, and how they can be inhibited. These membrane-embedded systems have exceptional biomedical importance as they play crucial roles in the spread of antibiotic resistance genes among bacterial pathogens.

Representative Publications:

Williams et al., (2025). Nature comms. 16(1):4906.

K. Macé et al., (2022). Nature, 607, 191-196.

A. Ilangovan et al., (2017). Cell. 169, 708–721.

T. Costa et al., (2016). Cell. 166, 1436–1444.

More can be learned at https://people.ismb.lon.ac.uk/gabriel-waksman/homepage.htm

We offer an international, creative, and inspiring environment. The successful candidates will benefit from our large network of collaborations and have immediate opportunities to contribute to international projects.

Open Positions

Postdoctoral Fellows

We are seeking:

1- Two Postdoctoral Fellow positions with specialism in cryo-Electron Microscopy and

2- Two Postdoctoral Fellow positions with specialism in Fluorescence Microscopy.

Qualifications

For the Postdoctoral Fellow positions with specialism in cryo-Electron Microscopy, applicants should have a PhD in Biophysics, X-ray Crystallography. Structural Biology, Biochemistry or related areas, and preferably (but not exclusively) extensive experience in cryo-Electron Microscopy data collection and processing. Excellent knowledge of molecular biology is essential. Working knowledge of the English language and willingness to improve language skills is essential.

For the Postdoctoral Fellow positions with specialism in Fluorescence Microscopy, applicants should have a PhD in Molecular and Cell MicroBiology or related areas, and preferably extensive experience in Fluorescence Microscopy data collection and processing as applies to live imaging of bacterial cells. Excellent knowledge of molecular biology is essential. Working knowledge of the English language and willingness to improve language skills is essential.

Main responsibilities

Research and Scholarship

· To characterize structural and functional features of multicomponent complexes involved in DNA transfer by conjugative type IV secretion systems (T4SS). This will require the postdoctoral scholars to participate in designing and carrying out experiments aiming to determine and dissect the molecular mechanism of the transport machinery.

· For both experimental design and interpretation of results, extensive scientific interactions with the collaborating laboratories will be essential.

· To conduct individual and collaborative research projects and write up research for publication.

· To update knowledge and understanding in field or specialism.

· To translate knowledge of advances in the subject area into research activity.

Teaching and Learning

· To contribute to the assessment of PhD student knowledge and supervision of their projects.

· To assist in the development of PhD student research skills and projects.

To supervise PhD student work.

People Management and Teamwork

· To manage own research and administrative activities, with guidance if required.

· To work with colleagues on joint projects is essential.

· To collaborate with academic colleagues on areas of shared research interest.

· To attend and contribute to relevant meetings.

· To assume organizational roles in lab management.

Problem Solving and Impact

· To use new research techniques and methods.

· To use own initiative and creativity to identify areas for research, develop new research methods, and extend the research portfolio.

· To use expertise to analyse and interpret research data and draw conclusions on the outcomes.

· To contribute to collaborative decision making with colleagues in areas of research.

Compensation and Benefits

a. Competitive salary based on the applicant’s work experience and ability (salary negotiable).

b. Social insurance and housing fund, supplementary medical insurance, physical examination and paid annual leave.

c. Opportunities for career development and available professional guidance.

How to apply

Please send (written in the English language): a resume, a brief summary of key accomplishments, the names and contacts of 3 referees and other materials demonstrating research capabilities to gabriel.waksman@cimrbj.ac.cn, and indicate the applicant's name and specific job position in the email subject.

This recruitment is valid for the long term until a suitable candidate is recruited.

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原文出处：

https://mp.weixin.qq.com/s/YTs5RkJ5DTCe0U10WDHEXQ

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